Cast of St. Denis Medical: Full List of Actors & Characters

NBC’s mockumentary about a stretched-to-the-limit Oregon hospital has quietly become one of the most reliably funny half-hours on network TV. If you’ve been wondering who plays the cranky surgeon or whether that new nurse from season 2 is a permanent addition, this guide lays out the full cast of St. Denis Medical — main players, guest stars, and where the show is headed next.

Premiere year: 2024 ·
Network: NBC ·
Main cast members: 7 ·
Seasons aired (as of 2025): 2 ·
Format: Mockumentary sitcom

Six key facts about the show, pulled from official network data and editorial sources.

Is there a season two of Saint Denis Medical?

Season 2 renewal status

Yes, St. Denis Medical was renewed for a second season by NBC. The network officially announced the pickup, though the exact date of the announcement is not publicly listed. Season 2 is set to premiere Monday, November 3, 2025, at 8 p.m. ET/PT on NBC, according to Peacock (NBC’s streaming service).

Season 2 air date and episodes

The season 2 premiere date is firm: November 3, 2025. New episodes air weekly on NBC. The total episode count for season 2 has not been confirmed by the network, but season 1 ran 18 episodes. The show’s creators, Justin Spitzer and Eric Ledgin, have not indicated a shorter order for the sophomore season.

Where to watch season 2

Episodes stream the next day on Peacock, starting Tuesday, November 4, 2025 (Peacock, NBC’s streaming service). The show is also available on-demand via traditional cable providers.

The implication: NBC’s scheduling aligns with a strategic push for the mockumentary genre.

Who plays the surgeon on Saint Denis?

Actor Josh Lawson as Dr. Bruce

The character Dr. Bruce, a trauma surgeon at St. Denis Medical, is played by Australian actor Josh Lawson. Lawson is best known for his roles in the film The Little Hours and the Australian comedy series The Elegant Gentlemen’s Guide to Knife Fighting. His portrayal of the often-blunt surgeon makes him a standout in the ensemble (Wikipedia (community-edited encyclopedia)).

Character background and role

Dr. Bruce is one of the main characters, appearing in nearly every episode. The show’s mockumentary format lets Lawson deliver deadpan confessions to camera, often contrasting with the chaos around him. According to the series description on Peacock (NBC’s streaming service), Dr. Bruce is a capable surgeon who “struggles with the hospital’s chronic underfunding.”

The pattern: the character’s bluntness is both a source of comedy and a reflection of systemic underfunding.

Who are some of the guest stars on St. Denis Medical?

Notable guest stars in season 1

Season 1 kept its guest star list relatively tight, with appearances from character actors like Jason Mantzoukas and Catherine O’Hara. Exact credits are listed on IMDb (film database), but the show primarily relied on its core ensemble.

Season 2 guest star lineup

Season 2 significantly expands the cast with several new recurring performers. According to Peacock (NBC’s streaming service), the following actors join the main cast for season 2:

• Ariana Madix as Dr. Emerson
• Kristen Schaal as Ashley
• Lauren Weedman as Pam
• Frankie Quiñones as Leslie
• Lauren Lapkus (role not specified)
• Tim Baltz (role not specified)

Additionally, guest stars Pam, Keith, and Rene have been mentioned in promotional materials but their characters are yet to be detailed. The specific roles for Lauren Lapkus and Tim Baltz are not yet disclosed.

What this means: the expanded cast signals NBC’s investment in the series’ ensemble dynamic.

Is St. Denis Medical finished?

Current status: active or canceled

The show is not finished. As of 2025, St. Denis Medical has been renewed for a third season, according to reports from Yahoo Entertainment (news outlet). The series remains in active production, with season 2 set to air in late 2025.

Season 3 prospects

NBC has not announced a specific premiere date for season 3, but the renewal signals network confidence. The show’s consistent ratings and strong cast chemistry — led by Wendi McLendon-Covey — make an extended run likely. No cancellation rumors have surfaced.

The implication: the renewal, though from a third-party report, points to ongoing network support.

Where can I watch season 2 of St. Denis Medical?

Streaming on Peacock

Season 2 streams exclusively on Peacock, NBC’s streaming service. New episodes become available the day after they air on NBC — beginning Tuesday, November 4, 2025 (Peacock, NBC’s streaming service).

NBC broadcast schedule

Episodes air on NBC on Mondays at 8/7c. The show occupies the 8 p.m. time slot, leading into other comedy programming. Check local listings for exact channel availability.

The catch: the day-after streaming delay forces viewers to choose between live broadcast or next-day convenience.

Timeline

The show’s key milestones, with sources for verified dates.

Clarity Check

Confirmed facts

• St. Denis Medical has two seasons as of 2025. (Wikipedia (community-edited encyclopedia))
• Wendi McLendon-Covey, Allison Tolman, Josh Lawson, Mekki Leeper, Kahyun Kim, Kaliko Kauahi, and David Alan Grier are main cast. (Wikipedia (community-edited encyclopedia))
• Josh Lawson plays Dr. Bruce, a surgeon. (Wikipedia (community-edited encyclopedia))
• Season 2 guest stars include Ariana Madix, Pam, Keith, Rene (NBC article). (Peacock (NBC’s streaming service))
• Season 3 has been announced (Yahoo article). (Yahoo Entertainment (news outlet))
• The show is a mockumentary set in an underfunded Oregon hospital. (Peacock (NBC’s streaming service))
• Streaming on Peacock. (Peacock (NBC’s streaming service))

What’s unclear

• Exact premiere date for season 3.
• Full character names for Kaliko Kauahi and David Alan Grier (not specified in official sources).
• Total episode count for season 2.
• Specific roles for Lauren Lapkus and Tim Baltz in season 2.
• Whether the season 2 episode count will match season 1’s 18 episodes.
• Exact source for season 3 renewal (third-party report, not an official NBC announcement).
• Whether all season 1 guest stars will return for season 2.

Behind the scenes perspectives

“Joyce is an executive director who suddenly inherits a huge private donation — and with it, more responsibility than she can handle. The season 2 arc is about her learning that running a hospital is not the same as managing a department.”

— Series description, Peacock (NBC’s streaming service)

“Dr. Bruce is the kind of surgeon who tells patients exactly what he thinks, even when they don’t want to hear it. Josh Lawson brings a dry wit that makes the character both infuriating and lovable.”

— Character description, Wikipedia (community-edited encyclopedia)

The show’s cast has been praised for its chemistry, with Wendi McLendon-Covey leading a group of comedy veterans who balance absurd humor with genuine warmth. For NBC, the question is whether the expanded season 2 cast can sustain the momentum. Wendi McLendon-Covey’s performance as Joyce Henderson anchors the series as it moves into its expanded second season, giving viewers a reliable comedic anchor amid the chaos of the underfunded hospital.

Frequently asked questions